WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 



User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: .05, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:molecular function       Name:NAD+ binding       ID:GO:0070403
C=12; O=2; E=0.04; R=46.32; rawP=0.0008; adjP=0.0384
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077463 NA SIRT6 sirtuin 6 51548 ENSG00000077463
2  ENSG00000187531 NA SIRT7 sirtuin 7 51547 ENSG00000187531


Database:molecular function       Name:protein deacetylase activity       ID:GO:0033558
C=18; O=2; E=0.06; R=30.88; rawP=0.0019; adjP=0.0384
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077463 NA SIRT6 sirtuin 6 51548 ENSG00000077463
2  ENSG00000187531 NA SIRT7 sirtuin 7 51547 ENSG00000187531


Database:molecular function       Name:NAD-dependent histone deacetylase activity       ID:GO:0017136
C=15; O=2; E=0.05; R=37.05; rawP=0.0013; adjP=0.0384
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077463 NA SIRT6 sirtuin 6 51548 ENSG00000077463
2  ENSG00000187531 NA SIRT7 sirtuin 7 51547 ENSG00000187531


Database:molecular function       Name:NAD-dependent protein deacetylase activity       ID:GO:0034979
C=16; O=2; E=0.06; R=34.74; rawP=0.0015; adjP=0.0384
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077463 NA SIRT6 sirtuin 6 51548 ENSG00000077463
2  ENSG00000187531 NA SIRT7 sirtuin 7 51547 ENSG00000187531


Database:molecular function       Name:histone deacetylase activity       ID:GO:0004407
C=17; O=2; E=0.06; R=32.69; rawP=0.0017; adjP=0.0384
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077463 NA SIRT6 sirtuin 6 51548 ENSG00000077463
2  ENSG00000187531 NA SIRT7 sirtuin 7 51547 ENSG00000187531





WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).